Always Encrypted using Microsoft.Data.SqlClient

Connection string

This Microsoft SqlClient Data Provider for SQL Server connection string can be used for connections to SQL Server 2019, SQL Server 2017, SQL Server 2016 and Azure SQL Database.

Data Source=myServer;Initial Catalog=myDB;Integrated Security=true;
Column Encryption Setting
=enabled;

This one is available in .NET Core (as opposed to System.Data.SqlClient).